Endocrine Abstracts

Background: Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) is defined as aplasia or hypoplasia of the uterus and vagina in female with normal 46,XX karyotype. Isolated congenital absence of the uterus and vagina is classified as MRKHS type 1 (typical form). If it is associated with at least one concomitant congenital malformation that mainly affect the renal and skeletal system, is classified as MRKHS type 2 (atypical form). We report here the cases of MRKH type 2 with i...

Introduction: Although the cause and effect relationship between the hypophyseal deficiency and osteoporosis is known well, the number of studies concerning bone mineral density (BMD) in patients with Sheehan’s syndrome (SS) are scarce. We aimed to investigate the relationship between BMD and deficient hormones in patients with newly-diagnosed Sheehan’s syndrome.Material and methods: Thirty-four patients with SS and age-gender-weight matched 22...

Background/aim: Visceral obesity rather than generalized obesity has been recognized as a risk factor for development of colonic adenomatous polyps. We aimed to to find out whether there is association between the obesity parameters determined by TANITA such as fat percent, body mass index (BMI) and visceral fat rating and prevalence of colonic adenomatous polyps.Material and methods: We conducted a cross-sectional study using a consecutive series of 231...

Endocrine Connections, 2018, 7(10): 1031–1039 (DOI: https://doi.org/10.1530/EC-18-0296)...

Introduction: Silent corticotroph adenomas (SCAs) are uncommon pituitary tumors, immunoreactive for ACTH, but without clinical evidence of hypercortisolism and present with local mass effects and some endocrine dysfunction. Case 43 years old male patient was diagnosed with pituitary tumor which was 5×3 cm in size. In history, 6 months ago he applied to another hospital with syncope and operated transsphenoidally. But these datas are unreachable. He had been suffering from...

Introduction: Parathyroid carcinoma is a rare malignancy of the parathyroid glands. Parathyroid carcinoma may be suspected, but it usually cannot be confirmed prior to operation.Case: A 35-year-old male was consulted to Endocrinology department with persistant kidney stones. He was operated five times in 10 years for recurrent kidney stones.His lab results are as follows; Ca:13(8.8–10.6), P:2.2 mg/dl(2.5–4.5), ALP:84U/L(3...

Introduction: Osteoporosis is a disease that is characterized by bone mass loss and deterioration in bone micro-architecture. One of the most important risk factors is dietary habits. The effects of the amount of calcium intake via eating, and low calcium consumption on the development of osteoporosis is still an active research area. The intestinal absorption of calcium and its renal excretion are still not understood very well. Even though the effects of carbohydrates on cal...

Introduction: Wegener granulomatosis is a necrotizing granulomatous small-vessel vasculitis. It typically affects the upper respiratory tract, lungs, and kidneys but can involve virtually any organ including the pituitary. Pituitary involvement in wegener granumatosis is rare.Case: A 50-year-old woman was admitted to the hospital with severe dyspne for 2 years and stridor for a month. During her hospitalization, her sodium level was noted to be persisten...

Introduction: Fibrates are widely used to manage dyslipidemia but these drugs can induce rhabdomyolysis with acute renal failure. Rhabdomyolysis is a skeletal muscle cell damage condition associated with the release of toxic components of the cells and to the end;renal failure. The onset of rhabdomyolisis can extend to 6 months with fibrate therapy. Some researchers purpose that the influenza vaccıne can induce the rhabdomyolisis in patients who receive myotoxic drugs.Her...

Introduction: The beneficial effects of vitamin D against gastrointestinal polyps and cancer in the gastrointestinal system as a whole remain unknown and relevance in repeat populations remain contraversial. Also in most studies the role of accompanying hypocalcemia itself is often neglected. For this reason we included only patients with low vitamin D levels and investigated the presence of gastric and colonic polyps.Methods/design: Between March 2011 a...